Dermatology 2008

Alitretinoin

• Appel K. Hand eczema: New therapy option with alitretinoin. Aktuel Dermatol. 2008; 34(8-9): 296.
• Cheng C, Michaels J, Scheinfeld N. Alitretinoin: a comprehensive review. Expert Opin Investig Drugs. 2008; 17(3): 437-443.
• Coenraads PJ. Alitretinoin in hand eczema. Ned Tijdschr Dermatol Venereol. 2008; 18(9): 354.
• Gensthaler BM. Relieving unbearable hand eczema with alitretinoin. Pharm Ztg. 2008; 153(31): 28.
• Molin S, Ruzicka T. Alitretinoin. A new treatment option for chronic refractory hand eczema. Hautarzt. 2008; 59(9): 703-709.
• Ruzicka T, Lynde CW, Jemec GBE, Diepgen T, Berth-Jones J, Coenraads PJ, Kaszuba A, Bissonnette R, Varjonen E, Holló P, Cambazard F, Lahfa M, Elsner P, Nyberg F, Svensson A, Brown TC, Harsch M, Maares J. Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: Results of a randomized, double-blind, placebo-controlled, multicentre trial. Br J Dermatol. 2008; 158(4): 808-817.
• Ruzicka T. Five questions about alitretinoin (Toctino®) for the treatment of severe refractory chronic hand eczema. Haut. 2008; 19(5): 214.
• Schienger R. Alitretinoin is supposed to cure chronic hand eczema. Dtsch Apoth Ztg. 2008; 148(38): 34-35.

17th Congress of the European Academy of Dermatology and Venereology EADV, September 2008, Paris, France

• FP-1601 / Insights into understanding the mechanisms of action of alitretinoin in chronic hand eczema. Homey B, Buenemann E, Wiesner U, Schmitt-Hoffmann A, Maares J, Ruzicka T.
• FP-1611 / Influence of food on the pharmacokinetics of oral alitretinoin (9-cis retinoic acid; BAL4079). Schmitt-Hoffmann A, Roos B, Kovacs P, Brown T, Maares J.
• FP-1619 / Comparability of physician and patient assessments of disease following treatment with alitretinoin (9-cis retinoic acid) in chronic hand eczema. Coenraads PJ, Diepgen T, Maares J, Brown T.
• FP-1620 / Pharmacokinetics, efficacy and safety of alitretinoin (9-cis retinoic acid) in moderate or severe refractory chronic hand eczema. Coenraads PJ, van der Wetering J, Roos B, Schmitt-Hoffmann AH.