Hebeisen P, Heinze-Krauss I,
Angehrn P, Hohl P, Page MG, Then RL.
In vitro and in vivo properties of Ro
63-9141, a novel broad-spectrum
cephalosporin with activity against
methicillin-resistant staphylococci.
Antimicrob Agents Chemother. 2001;
45(3): 825–36.
Bowker KE, Wootton M, Holt HA and
MacGowan AP. In Vitro Activity of Ro
63-9141, a Novel Broad Spectrum
Pyrolidinone Cephalosporin: Activity
Against Clinically Significant
Anaerobes. 38th ICAAC 1998. Poster
F-020.
Hebeisen P, Goetschi E, Gross G,
Heinze-Krauss I, Hubschwerlen C,
Schmitt-Hoffmann AH, Theil F-P,
Specklin J-L. Synthesis,
Physicochemical and Pharmacokinetic
Properties of Water-Soluble Prodrugs
of Ro-63-9141. 38th ICAAC 1998.
Poster F-026.
Heinze-Krauss I, Angehrn P,
Charnas RL, Gubernator K, Gutknecht
EM, Hubschwerlen C, Kania M, Oefner
C, Page MG, Sogabe S, Specklin JL,
Winkler F. Structure-based design of
beta-lactamase inhibitors. 1.
Synthesis and evaluation of bridged
monobactams. J Med Chem. 1998;
41(21): 3961–71.
Hohl P, Angehrn P, Then RL,
Hebeisen P, Heinze-Krauss I. Ro
63-9141, a Novel Broad-Spectrum
Anti-MRSA Pyrrolidinone
Cephalosporin. Part I: Activity
Against Aerobic Gram-Negatives. 38th
ICAAC 1998. Poster F-024.
Page M, Bur D, Danel F,
Heinze-Krauss I, Kania M, Mensch B,
Runtz V, Weiss, Winkler F. Inhibition
of the Penicillin-binding Proteins of
Methicillin-resistant Staphylococci
by Pyrrolidinone-3-ylidenemethyl
Cephems. 38th ICAAC 1998. Poster
F-22.
Theil F-P, Schönlein P,
Schenk A, Schmitt-Hoffmann A.
Pharmacokinetics of the Cephalosporin
Ro 63-9141 in Five Animal Species
– Extrapolation to Man. 38th
ICAAC 1998. Poster F-025.
Zbinden R, Puenter V, von
Graevenitz A. Ro63-9141, a Novel
Broad-Spectrum anti-MRSA
Pyrrolidinone Cephalosporin. Activity
against Gram-negative Nonfermenters.
38th ICAAC 1998. Poster
F-019.
Heinze-Krauss I, Angehrn P,
Guerry P, Hebeisen P, Hubschwerlen C,
Kompis I, Page MG, Richter HG, Runtz
V, Stalder H, Weiss U, Wie CC.
Synthesis and Structure-Activity
Relationship of (Lactamylvinyl)
Cephalosporins Exhibiting Activity
against Staphylococci, Pneumococci,
and Enterococci. J Med Chem. 1996;
39(9): 1864–71.